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pentobarbital will reduce the level or effect of amlodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.pentobarbital will lessen the level or effect of atogepant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Advised atogepant dosage with concomitant utilization